The reaction of organozinc reagents with trifluoroacylated phosphonates: Synthesis of trifluoromethylated α, β-unsaturated esters with an active methylene moiety
✍ Scribed by Yanchang Shen; Jiahong Ni
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 85 KB
- Volume
- 15
- Category
- Article
- ISSN
- 1042-7163
- DOI
- 10.1002/hc.20018
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✦ Synopsis
Abstract
The consecutive reaction of phosphonates 1 with n‐butyllithium, trifluoroacetic anhydride, and organozinc compounds gives trifluoromethylated α,β‐unsaturated esters with an active methylene moiety and predominant Z‐selectivity in 54–78% (3 steps) yields. © 2004 Wiley Periodicals, Inc. Heteroatom Chem 15:289–292, 2004; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20018
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v