✦ LIBER ✦
The reaction of dimethyl β-ketoglutarate with 1,2-dicarbonyl compounds. III. Exo-tetracyclo[5.5.1.02,6.010,13]tridecane-4,8,12-trione
✍ Scribed by Kenner C. Rice; Norman E. Sharpless; Ulrich Weiss; Robert J. Highet
- Publisher
- Elsevier Science
- Year
- 1975
- Tongue
- French
- Weight
- 182 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
✦ Synopsis
We have reported earlier2$3 that reaction of dimethyl B-ketoglutarate (_I) with glyoxal
(2) in slightly acidic aqueous solution at room-temperature yields a precipitate of cyclic Bketo esters, Acid-catalyzed hydrolysis and decarboxylation of these intermediates gave bicyclo-