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The Reaction of Cyclohexan-1,3-dione with Cyanomethylenes: Synthesis of Thiophenes and Their Fused Derivatives with Antifungal Activities

โœ Scribed by Mohareb, Rafat M.; Sherif, Sherif M.; Moustafa, Hosam El-Dean


Book ID
120345828
Publisher
Taylor and Francis Group
Year
2009
Tongue
English
Weight
361 KB
Volume
184
Category
Article
ISSN
1042-6507

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Reaction of 4-aryl-3-thiosemicarbazides
โœ Rafat M. Mohareb; Sherif M. Sherif ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 203 KB ๐Ÿ‘ 2 views

The reaction of 3-aryl-3-thiosemicarbazides 1a-d with carbon disulfide in alkaline medium affords the nonisolable sulfide salts 2a-d. The latter undergo in situ heterocyclization with some โฃ-halogenated compounds, e.g., 3a,b and 13, to afford polyfunctionally substituted 2,3-dihydrothiazoles 4a-e an