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The reaction of 1-azirines with 2-pyridyl isothiocyanate: Possible approaches to benzodiazepine and benzodiazepine derivatives

✍ Scribed by V. Nair; K. H. Kim


Book ID
112123827
Publisher
Journal of Heterocyclic Chemistry
Year
1976
Tongue
English
Weight
239 KB
Volume
13
Category
Article
ISSN
0022-152X

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## 1,5-benzodiazepines / Cyclizations / Cycloadditions The reaction of o-phenylenediamine (4) with one, two or three equivalents of p-substituted 3-dimethylaminopropiophenone hydrochlorides 5a-e was studied. 4-Aryl-2,3-dihydro-1H-1,5-benzodiazepine derivatives 6a-e were obtained in good yields, alo