✦ LIBER ✦

The Reaction Mechanism of Spirocylization and Stereoselectivity Studies for the Calyculin C16–C25 Fragment

✍ Scribed by Vesa Rauhala; Kalle Nättinen; Kari Rissanen; Ari M. P. Koskinen

Publisher: John Wiley and Sons
Year: 2005
Tongue: English
Weight: 186 KB
Volume: 2005
Category: Article
ISSN: 1434-193X
DOI: 10.1002/ejoc.200500206

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

The mechanism of the double intramolecular hetero‐Michael addition, a key reaction in the planned synthesis of the natural product calyculin C, has been studied by NMR. The cyclization follows Baldwin’s rules and proceeds first through a six‐membered ring closure (6‐endo‐dig), followed by a five‐membered ring cyclization (5‐exo‐trig). (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005)

📜 SIMILAR VOLUMES

ChemInform Abstract: Studies Directed To

ChemInform Abstract: Studies Directed Toward the Total Synthesis of Azaspiracid: Stereoselective Construction of C1—C12, C13—C19, and C21—C25 Fragments.

✍ Rich G. Carter; David J. Weldon 📂 Article 📅 2001 🏛 John Wiley and Sons ⚖ 31 KB 👁 2 views

ChemInform Abstract: Studies of Fragment

ChemInform Abstract: Studies of Fragment Assembly Aldol Reactions of Chiral Aldehydes and Chiral Methyl Ketones: Stereoselective Synthesis of the C(13)—C(25) Segment of Scytophycin C.

✍ William R. Roush; Garrett J. Dilley 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 28 KB 👁 2 views

Concise and Stereoselective Synthesis of

Concise and Stereoselective Synthesis of the N7—C25 Fragment of Psymberin (I).

✍ Jason C. Rech; Paul E. Floreancig 📂 Article 📅 2006 🏛 John Wiley and Sons ⚖ 12 KB

ChemInform Abstract: Studies on the Tota

ChemInform Abstract: Studies on the Total Synthesis of Macrolactin A. A Stereoselective Synthesis of the C3—C13 and C14—C24 Fragments.

✍ Shukun Li; Rui Xu; Donglu Bai 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 33 KB 👁 2 views

Synthetic Studies on Bafilomycin A1: Ste

Synthetic Studies on Bafilomycin A1: Stereoselective Synthesis of the C12—C17 Fragment (I) and Its Coupling with the C1—C11 Subunit.

✍ Emmanuelle Queron; Robert Lett 📂 Article 📅 2004 🏛 John Wiley and Sons ⚖ 55 KB 👁 1 views

ChemInform Abstract: Isotope Effects for

ChemInform Abstract: Isotope Effects for 18F and 11C in the Study of Reaction Mechanisms

✍ Olle Matsson; Susanna MacMillar 📂 Article 📅 2008 🏛 John Wiley and Sons ⚖ 15 KB 👁 2 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v