The rationale for deltanoids in therapy for myeloid leukemia: Role of KSR–MAPK–C/EBP pathway
✍ Scribed by George P. Studzinski; Xuening Wang; Yan Ji; Qing Wang; Yingyu Zhang; Andrzej Kutner; Jonathan S. Harrison
- Book ID
- 116697667
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 643 KB
- Volume
- 97
- Category
- Article
- ISSN
- 0960-0760
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Data demonstrating the superiority of nilotinib over imatinib in the frontline treatment of chronic myeloid leukemia (CML) and ongoing studies with dasatinib and bosutinib are rapidly changing the treatment landscape for CML. In this review, the authors discuss currently available thera
## Abstract Fas and FasL expression upregulation was found in human leukemia K562 cells upon exposure to __Naja naja atra__ phospholipase A~2~ (PLA~2~). PLA~2~ treatment induced an increase in intracellular Ca^2+^ ([Ca^2+^]i) and ROS generation levels, leading to activation of p38 MAPK and JNK. Sup