## Abstract When replicating DNA is labeled sequentially with radioactive and density tracers and analyzed by equilibrium centrifugation, the fraction banding at heavier than normal density is inversely proportional to the rate of replication fork movement if there is a sharp transition from one tr
The rate of fork movement during DNA replication in mammalian cells
β Scribed by Yu. B. Yurov
- Publisher
- Springer
- Year
- 1979
- Tongue
- English
- Weight
- 775 KB
- Volume
- 74
- Category
- Article
- ISSN
- 0009-5915
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During DNA synthesis there is a distinct stage immediately after the joining of large DNA replication intermediates (post-elongation stage). The conversion of this DNA to mature DNA was analysed in cells treated with aphidicolin to stop the movement of the replication fork. In such cells mature DNA