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The question of differential hydrogen bonding in the mechanism of catalysis by serine proteases

✍ Scribed by Peter Campbell; Nashaat T. Nashed


Publisher
Elsevier Science
Year
1978
Tongue
English
Weight
538 KB
Volume
7
Category
Article
ISSN
0045-2068

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Conserved water molecules in the specifi
✍ Maxwell M. Krem; Enrico Di Cera πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 276 KB πŸ‘ 2 views

Conservation of clusters of buried water molecules is a structural motif present throughout the serine protease family. Frequently, these clusters are shaped as water channels forming extensive hydrogen-bonding networks linked to the protein backbone. The most conspicuous example is the water channe