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The Quantitative Distinction of Hyperplasia from Hypertrophy in Hepatomegaly Induced in the Rat Liver by Phenobarbital

✍ Scribed by Philip Carthew; Richard E. Edwards; Barbara M. Nolan

Book ID
112268774
Publisher
Oxford University Press
Year
1998
Tongue
English
Weight
151 KB
Volume
44
Category
Article
ISSN
1096-6080

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The onset of sodium retention in phenobarbitalharbon tetrachloride-induced cirrhosis in rats is preceded by a linear decrease in hepatic function as assessed by the aminopyrine rate constant of elimination. Sodium retention occurs when liver function decreases below a critical aminopyrine rate const