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The Puzzling Role of CXCR3 and Its Ligands in Organ Allograft Rejection

✍ Scribed by P. F. Halloran; R. L. Fairchild

Book ID
114804832
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
55 KB
Volume
8
Category
Article
ISSN
1600-6135

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## Abstract NKG2D is a receptor expressed by NK cells and subsets of T lymphocytes. On NK cells, NKG2D functions as a stimulatory receptor that induces effector functions. We cloned and expressed two rat NKG2D ligands, both members of the RAE1 family, RAE1L and RRLT, and demonstrate that these liga