## Abstract Although radiolytic decomposition of several radiopharmaceuticals has exhibited apparent firstβorder kinetics, the dependence of decomposition on drug concentration precludes a firstβorder rate process. A kinetic study of the decomposition of ^131^Iβoβiodohippurate in aqueous solution w
β¦ LIBER β¦
The purity stabilisation of sodium o-iodohippurate (131I)
β Scribed by I. Lisewska; A. Pasternak; K. Zelenay
- Publisher
- John Wiley and Sons
- Year
- 1971
- Tongue
- French
- Weight
- 155 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0022-2135
No coin nor oath required. For personal study only.
β¦ Synopsis
To prevent the autoradiolysis damage in sodium o-iodohippurate-1311 preparations, various conditions of storage have been tested: storage in isotonic solution frozen at dry ice temperature, and in freeze-dried state. A preparation which was stable ,for the guarantee period of about 1 month was obtained by storing it frozen at the temperature about -700 C. The stability of sodium o-iodoh i p p u r ~t e -~3 ~1 was compared with that of the similar compound labelled with iodine-125.
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