The purification of haematoporphyrin IX and its acetylated derivatives
β Scribed by C. Vever-Bizet; O. Delgado; D. Brault
- Book ID
- 104144725
- Publisher
- Elsevier Science
- Year
- 1984
- Tongue
- English
- Weight
- 498 KB
- Volume
- 283
- Category
- Article
- ISSN
- 1873-3778
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β¦ Synopsis
The purification of haematoporphyrin IX by extraction followed by chromatography on silica gel is described. Thin-layer chromatography and NMR spectroscopy confirmed the high purity of the haematoporphyrin thus obtained. The different components of acetylated haematoporphyrin and those of haematoporphyrin derivative (HpD), a material used in cancer phototherapy, were also separated on silica gel.
π SIMILAR VOLUMES
PMR spectra of d-aldosterone, its acetylated derivatives and related compounds were studied using 60 and 100 MHz spectrometers at various temperatures, in CDCI,, DMSO-d,,, CD30D and DzO. The aldehyde form (1) was not found. The solutions of d-aldosterone and aldosterone-21 acetate contain a mixture