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The purification of haematoporphyrin IX and its acetylated derivatives

✍ Scribed by C. Vever-Bizet; O. Delgado; D. Brault


Book ID
104144725
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
498 KB
Volume
283
Category
Article
ISSN
1873-3778

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✦ Synopsis


The purification of haematoporphyrin IX by extraction followed by chromatography on silica gel is described. Thin-layer chromatography and NMR spectroscopy confirmed the high purity of the haematoporphyrin thus obtained. The different components of acetylated haematoporphyrin and those of haematoporphyrin derivative (HpD), a material used in cancer phototherapy, were also separated on silica gel.


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