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The pur3 gene from the pur cluster encodes a monophosphatase essential for puromycin biosynthesis in Streptomyces

✍ Scribed by María Blanca Sánchez; Patricia Barrado; Antonio Jiménez; María Fernández Lobato


Book ID
116466464
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
152 KB
Volume
580
Category
Article
ISSN
0014-5793

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A central segment of a cluster of biosynthetic genes for the antibiotic streptomycin cloned from Streptomyces griseus was analysed for open reading frames, as well as for transcriptional and translational activity. The nucleotide sequence revealed two significant open reading frames, ORF1 and APH(6)