The psychoneuroimmunology of depression
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Brian E. Leonard; Ayemu Myint
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Article
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2009
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John Wiley and Sons
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English
β 127 KB
## Abstract Chronic stress, by initiating changes in the hypothalamicβpituitaryβadrenal (HPA) axis and the immune system, acts as a trigger for anxiety and depression. There is experimental and clinical evidence that the rise in the concentration of proβinflammatory cytokines and glucocorticoids, w