The pseudorotational interconversion of the furanose ring conformers in nucleic acids
β Scribed by Camillo Tosi; Wolfram Saenger
- Publisher
- Elsevier Science
- Year
- 1982
- Tongue
- English
- Weight
- 427 KB
- Volume
- 90
- Category
- Article
- ISSN
- 0009-2614
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π SIMILAR VOLUMES
We have used 2D NMR spectroscopy to study the sugar conformations of oligonucleotides containing a conformationally restricted nucleotide (LNA) with a 2'-O, 4'-C-methylene bridge. We have investigated a modified 9-mer single stranded oligonucleotide as well as three 9-and 10-mer modified oligonucleo
## Abstract Semiempirical conformational energy calculations have been performed on dinucleoside triphosphate models with and without base interactions to investigate the conformational requirement for the stereochemical and energetic feasibility of (__gauche__^+^,__gauche__^+^) phosphodiester conf