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The proα2 (V) collagen gene (COL5A2) maps to 2q14→2q32, syntenic to the proα1 (III) collagen locus (COL3A1)

✍ Scribed by Cécile Huerre-Jeanpierre; Isabelle Henry; M. Bernard; Pia Gallano; Dominique Weil; K. H. Grzeschik; F. Ramirez; Claudine Junien


Publisher
Springer
Year
1986
Tongue
English
Weight
374 KB
Volume
73
Category
Article
ISSN
0340-6717

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✦ Synopsis


A recombinant probe specific for the pro alpha 2 chain of human Type V collagen has been used for the localization of the corresponding gene (COL5A2) to chromosome 2. Regional mapping by in situ hybridization and analysis of DNA from human X rodent cell lines indicated that COL5A2 is confined within the segment 2q14----2q32, thus syntenic to the pro alpha 1 (III) collagen gene (COL3A1).