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The Protonation and Deprotonation Equilibria of Hypericin Revisited

✍ Scribed by Johann G. Leonhartsberger; Heinz Falk


Book ID
107706650
Publisher
Springer Vienna
Year
2002
Tongue
English
Weight
65 KB
Volume
133
Category
Article
ISSN
0026-9247

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Microscopic Protonation/Deprotonation Eq
✍ Krisztina TakΓ‘cs-NovΓ‘k; JΓ³zsef KΓΆkΓΆsi; BenjΓ‘min PodΓ‘nyi; BΓ©la NoszΓ‘l; Ruey-Shiua πŸ“‚ Article πŸ“… 1995 πŸ› John Wiley and Sons 🌐 German βš– 586 KB

The microscopic ionization behavior of piroxicam was investigated using two different approaches, ie., direct UV spectroscopy and an indirect analogue approach (deductive method). The best microscopic pK, values (pK,,, = 4.60, pK,,, = 5.40, pKa2, = 2.72, and pK,,, = 1.92) were obtained by the deduct