Methamphetamine (METH) is an amphetamine analog that produces degeneration of the dopaminergic system in mammals. The neurotoxic effects of the drug are thought to be mediated by oxygen-based free radicals. In the present report, we have used immortalized neural cells obtained from rat mesencephalon
โฆ LIBER โฆ
The proto-oncogene Bcl-2 and its role in regulating apoptosis
โ Scribed by Kroemer, Guido
- Book ID
- 109929875
- Publisher
- Nature Publishing Group
- Year
- 1997
- Tongue
- English
- Weight
- 305 KB
- Volume
- 3
- Category
- Article
- ISSN
- 1078-8956
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BCL-6 is an important regulator of the immune system. It is required for GC formation and T cell dependent antibody responses. Mice deficient in BCL-6 fail to form GC and mount reduced levels of T cell-dependent antibody responses. BCL-6 (-/-) mice, in addition, develop a massive inflammatory respon