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The Protein Nature of Enzymes. An Investigation of Pancreatic Lipase

โœ Scribed by Glick, David; King, C. G.


Book ID
126823226
Publisher
American Chemical Society
Year
1933
Tongue
English
Weight
362 KB
Volume
55
Category
Article
ISSN
0002-7863

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A model for the interfacial orientation and the mode of action of lipase is proposed. Lipase is oriented so that its active site is near the oil-water boundary. This orientation is achieved by oil-enzyme bonding at the "hydrophobic head" of the enzyme, a region free of electric charges and relativel