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The protein composition of honeybee venom reconsidered by a proteomic approach

✍ Scribed by Nico Peiren; Frank Vanrobaeys; Dirk C. de Graaf; Bart Devreese; Jozef Van Beeumen; Frans J. Jacobs

Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
137 KB
Volume
1752
Category
Article
ISSN
1570-9639

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✦ Synopsis

Pure honeybee venom samples were submitted to two-dimensional gel electrophoresis. A total of 49 excised spots were analyzed by mass spectrometry; 39 of them resulted in the identification of 6 different known bee venom proteins and of 3 proteins that have not been described in such samples before. The first new venom protein has a platelet-derived and vascular endothelial growth factor family domain, the second protein shows no homologies with any known protein and the third matches a hypothetical protein similar to major royal jelly protein 8.

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