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The protective role of antibody responses during Mycobacterium tuberculosis infection

โœ Scribed by F. Abebe; G. Bjune


Book ID
108701062
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
154 KB
Volume
157
Category
Article
ISSN
0009-9104

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IL-10 regulates the balance of an immune response between pathogen clearance and immunopathology. We show here that __Mycobacterium tuberculosis__ (__Mtb__) infection in the absence of IL-10 (IL-10^โˆ’/โˆ’^ mice) results in reduced bacterial loads in the lung. This reduction was preceded by an accelerat