## Abstract __Mycobacterium tuberculosis__ is the causative agent of pulmonary tuberculosis which has infected one third of the mankind and causes 2β3 million deaths worldwide each year. The persistence of the infection ensues from the ability of __M. tuberculosis__ to subvert host immune responses
The protective immune response to Mycobacterium tuberculosis
β Scribed by Andrea M. Cooper; JoAnne L. Flynn
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 547 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0952-7915
No coin nor oath required. For personal study only.
β¦ Synopsis
Recent advances have characterized the protective immune response against Mycobacterium tuberculosis. These include identification of the phenotype of some protective cells, the antigens to which these cells respond and the cytokines produced in response to infection which modulate disease. Progress has also been made in inducing this response by vaccination.
π SIMILAR VOLUMES
## Abstract Tuberculosis remains the most hazardous bacterial infection worldwide. The causative agent, __Mycobacterium tuberculosis__, is a facultative intracellular pathogen of resting MΞ¦. IFNβΞ³ secreted by natural killer, CD4 Th 1 and CD8 T cells upon instruction by ILβ12 and β18 activates MΞ¦ to
## Abstract __Mycobacterium tuberculosis__ bacilli are seldom demonstrated in tuberculous pleural effusion (TPE) by conventional bacteriological methods. In this study, an indirect enzymeβlinked immunosorbent assay (ELISA) was developed to detect IgG against four mycobacterial recombinant antigens
## Abstract The human immune response to tuberculosis (TB) is especially mediated by T CD4^+^lymphocytes. However, more studies are needed in order to understand the exact role of each cytokine in the mechanisms for cures. In this article, our aim was to analyze the production of TNFβΞ±, ILβ10, and