The prognostic value of CD44 expression in gastric cancer: A meta-Analysis
β Scribed by Chen, Yansu; Fu, Ziyi; Xu, Sujuan; Xu, Ye; Xu, Pengfei
- Book ID
- 127245084
- Publisher
- Elsevier Science
- Year
- 2014
- Tongue
- English
- Weight
- 533 KB
- Volume
- 68
- Category
- Article
- ISSN
- 0753-3322
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CD44 is a family of cell surface transmembrane glycoproteins members which differ in the extracellular part by sequences derived by alternative splicing of 10 variant exons (v1-v10). CD44 proteins containing such variant sequences have been implicated in tumor metastasis formation. Here, we have eva
In the present study, the expression and prognostic role of the CD44 splicing variants v5 and v6 were immunohistochemically investigated in 418 curatively resected gastric carcinomas. CD44v5 was expressed in 65β’3 per cent (n=273) and CD44v6 in 77β’0 per cent (n=322) of the tumours. Whereas the expres