The prognostic value of lymphocyte doubling time (LDT), expressed in months and obtained by means of a linear regression, has been studied in 99 previously untreated chronic lymphocytic leukemia (CLL) patients. LDT is defined as the period of time needed for lymphocytes to double in number the amoun
The prognostic value of bone marrow lymphocytes in acute lymphocytic leukemia of childhood
โ Scribed by Alexander A. Green
- Publisher
- John Wiley and Sons
- Year
- 1974
- Tongue
- English
- Weight
- 355 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0008-543X
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Bone marrow necrosis has been regarded as an indicator of very poor prognosis in malignant disease. The cause and incidence are unknown, and reports of treatment response are few. We describe four children with marrow necrosis at presentation with acute lymphocytic leukemia (ALL), all of whom entere
Although bone marrow biopsy pattern (BMBP) has long been suggested to be an independent prognostic factor in chronic lymphocytic leukemia (CLL), conflicting reports continue to appear in the literature. To investigate this issue we retrospectively reviewed 70 CLL patients who had undergone bone marr