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The production of foot-and-mouth disease virus from BHK 21 C 13 cells grown on the surface of DEAE sephadex A50 beads

✍ Scribed by R. E. Spier; J. P. Whiteside

Publisher
John Wiley and Sons
Year
1976
Tongue
English
Weight
347 KB
Volume
18
Category
Article
ISSN
0006-3592

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✦ Synopsis

Abstract

Methods are described which make possible the production of foot‐and‐mouth disease (FMD) virus from BHK 21 C13 monolayer cells which have been grown on the surface of serum coated DEAE Sephadex A50 beads. The yield of cells and their susceptibility to infection by FMD virus are equivalent to conventional Roux monolayer systems. The potential for the commercial application of the DEAE Sephadex A50 system is discussed in relation to other unit process monolayer systems and in particular to the system in which cells are cultured in a deep bed of small glass spheres.

📜 SIMILAR VOLUMES

The production of foot-and-mouth disease
The production of foot-and-mouth disease virus from BHK 21 C 13 cells grown on the surface of glass spheres
✍ R. E. Spier; J. P. Whiteside 📂 Article 📅 1976 🏛 John Wiley and Sons 🌐 English ⚖ 377 KB

## Abstract In view of the advantages which are associated with the use of the BHK monolayer cell for the production of foot‐and‐mouth disease (FMD) virus, a unit system using glass spheres was developed to grow BHK monolayer cells and to test the susceptibility of such cells to FMD virus. The yiel