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The pro-sequence domain of streptopain directs the folding of the mature enzyme

✍ Scribed by Elizabeth T. Anderson; Laurie A. Winter; Phil Fernsten; Stephen B. Olmsted; Yury V. Matsuka

Book ID
116177290
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
657 KB
Volume
436
Category
Article
ISSN
0003-9861

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πŸ“œ SIMILAR VOLUMES

Protease pro region required for folding
Protease pro region required for folding is a potent inhibitor of the mature enzyme
✍ David Baker; Joy L. Silen; Dr. David A. Agard πŸ“‚ Article πŸ“… 1992 πŸ› John Wiley and Sons 🌐 English βš– 582 KB

## Abstract α‐Lytic protease, an extracellular bacterial serine protease, is synthesized with a large pro region that is required in vivo for the proper folding of the protease domain. To allow detailed mechanistic study, we have reconstituted pro region‐dependent folding in vitro. The pro region p