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The pro-inflammatory potential of T cells in juvenile-onset systemic lupus erythematosus

✍ Scribed by Ballantine, Lucy E; Ong, Joanne; Midgley, Angela; Watson, Louise; Flanagan, Brian F; Beresford, Michael W

Book ID
121564710
Publisher
BioMed Central
Year
2014
Tongue
English
Weight
230 KB
Volume
12
Category
Article
ISSN
1546-0096

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## Abstract ## Objective Accumulation of apoptotic cells may lead to the development of systemic lupus erythematosus (SLE) through a breakdown in immune tolerance. Altered neutrophil apoptosis may contribute to nuclear autoantigen exposure, ultimately leading to autoantibody generation. This study