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The Pro- and Antioxidant Role of Glutathione in Selenite-induced Oxidative Stress and Apoptosis

✍ Scribed by Han-Ming Shen; Cheng-Feng Yang; Jin Liu; Choon-Nam Ong

Book ID
111397135
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
127 KB
Volume
928
Category
Article
ISSN
0890-6564

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The mechanisms involved in the anti-carcinogenic activity of selenium remain to be elucidated. In the present study, we examined sodium selenite-induced oxidative stress and apoptosis in a human hepatoma cell line (HepG 2 ). Sodium selenite (10 M) exerted clear cytotoxic effect, as shown by the sign