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The prion hypothesis in Parkinson's disease: Braak to the future

✍ Scribed by Visanji, Naomi P; Brooks, Patricia L; Hazrati, Lili-Naz; Lang, Anthony E


Book ID
120893125
Publisher
Springer (Biomed Central Ltd.)
Year
2013
Tongue
English
Weight
585 KB
Volume
1
Category
Article
ISSN
2051-5960

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## Abstract Braak and colleagues have proposed that, within the central nervous system, Parkinson's disease (PD) begins as a synucleinopathy in nondopaminergic structures of the lower brainstem or in the olfactory bulb. The brainstem synucleinopathy is postulated to progress rostrally to affect the