The prevalence of high-grade prostatic intraepithelial neoplasia in surgical resection specimens : An Indian experience
✍ Scribed by Sangeeta B. Desai; Anita M. Borges
- Publisher
- John Wiley and Sons
- Year
- 2002
- Tongue
- English
- Weight
- 41 KB
- Volume
- 94
- Category
- Article
- ISSN
- 0008-543X
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✦ Synopsis
Abstract
BACKGROUND
To the authors' knowledge there is a paucity of literature regarding the prevalence of high‐grade prostatic intraepithelial neoplasia (HGPIN) in the Indian subcontinent. The objective of the current study was to document the prevalence of HGPIN in a low‐risk Indian population.
METHODS
A total of 110 prostate specimens (61 taken from the test group and 49 taken from the control group) were studied to document the prevalence of HGPIN in a low‐risk Indian population.
RESULTS
None of the benign prostate samples were found to harbor HGPIN, whereas 85.24% of the samples from malignant prostates did so.
CONCLUSIONS
A strong correlation between HGPIN and invasive carcinoma was observed, a finding that reinforces the view that HGPIN is a strong indicator of concurrent invasive prostate carcinoma. Cancer 2002;94:2350–2. © 2002 American Cancer Society.
DOI 10.1002/cncr.10495