The present and the future of serotonergic drugs

✍ Scribed by Herman M. van Praag

• Publisher: John Wiley and Sons
• Year: 1991
• Tongue: English
• Weight: 550 KB
• Volume: 6
• Category: Article
• ISSN: 0885-6222
• DOI: 10.1002/hup.470060504

✦ Synopsis

5-HT uptake inhibitors have a definite place in the treatment of mood disorders, although their primary target is uncertain. Mood-, anxiety-, and aggression-regulation are the most likely candidates. 5-HT uptake inhibitors are also effective in Panic Disorder and OCD, where the primary target in PD is probably anxiety and in OCD either anxiety or aggression. It is recommended that 5-HT uptake blockers should be studied in aggression disorders. Furthermore, it is concluded that the range of indications of selective 5-HT uptake blockers can better be described dimensionally than nosologically, leading to a new era of clinical psychopharmacology, described as functional psychopharmacology .