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The Presence of (+)-S-Adenosyl-l-Methionine in the Rat Brain and Its Lack of Effect on Phenylethanolamine N-Methyltransferase Activity

✍ Scribed by Corinne Beaudouin; Gisèle Haurat; Jean Alex Laffitte; Bernard Renaud


Book ID
111177909
Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
768 KB
Volume
61
Category
Article
ISSN
0022-3042

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✍ Amparo Larrauri; José V. Castell; Guillermo Garrido; Joaquín Berenguer; M. José 📂 Article 📅 1992 🏛 Springer 🌐 English ⚖ 807 KB

In this study, ethinylestradiol inhibited the uptake of taurocholate by cultured rat hepatocytes, increasing the Krn while leaving the Vmax unchanged. S-Adenosyl-L-methionine (SAMe) had no effect on taurocholate uptake or release, but was able to reverse the competitive inhibition induced by ethinyl