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The preparation of octahydro leukotrienes C, D, and E via a stereoselective sulfenyllactonization reaction

✍ Scribed by Robert N. Young; William Coombs; Yvan Guindon; Joshua Rokach; Diane Ethier; Ronald Hall


Publisher
Elsevier Science
Year
1981
Tongue
French
Weight
283 KB
Volume
22
Category
Article
ISSN
0040-4039

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## Abstract A new method for the synthesis of highly deuterated or tritiated leukotrienes was developed. The higher reactivity of a terminal alkene compared to a 1,2‐disubstituted one permitted the selective deuteration or tritiation of the diyne 14,15,19,19,20,20‐hexadehydro LTC~4~ triester 1. Aft