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The preparation of iodine-containing x-ray contrast substances. III. The structure of “choloselectan”

✍ Scribed by Banker, Wilson ;Sansbury, H. ;Simmonds, W. H. C.


Publisher
Wiley (John Wiley & Sons)
Year
1943
Weight
299 KB
Volume
62
Category
Article
ISSN
0368-4075

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✦ Synopsis


CONTRAST SUBSTANCES. III. THE STRUCTURE OF CHOLOSELECTAN " By WILSON BAKER, H. SANSBURY, and (in part) W. H. C. SIMMONDS Clioloselectnn, n re]iiitccl S-ruv coiitrust for tlic pill blncl~ler. is atatcd to pos..cas foniiu~ii (I). I t nlq&irs to Irnvc ~l e r i ~ 1ircpwerI IIV tIio roil-~Ieiientiori of ioc~oisntin (11) wit~i 3 : ~-c~i-iirc~o-~-~-~igc~rosgeilic~sgiic~etopliciioiio (HI), nncl nltlioigli the ~~roiliict frorii this rciiction w i i H piveil atriictum (I'), it is itow sliow~i tlint I lie oiilv inolitblc clietiiir~il iiiiliviiliinl is tho siiiiplu hrivtitiw (V), tIic Iiydrvsgut;yl proiip being eIiiiiiiii~tci~ by ligclrolgsis rlitritig tliu i~oiiilci~aiitiori. Cl~oloselr~~trin WIIS ~~rob;ibIy tlic c a n i ~~~t t ~i ~I (V) iii II wry iriipiiru I I ~I I I ~.

Cliolosclcctrin, ii rcputerl .Y-r:iy ctiiitriist. for the g~ill l)liitltler, w t s first mciit.ioiic!cl 11y l'ril)rmi.* It wis stater1 to IJC t lie iotliniitetl 3-~~1ienylquititrlittc-~I-c~iirlrosylic iicitl deriviitivc (I), i t n i l II further reference to the cotnpotititl w i s rtintlc hy lIiiix,z hut since then Choloselcctiin liiis only liccri inrtitionctl Iwicfly Iiy I<leil)cr,:l \vho repnrteil tlittt nltliouglt it gave exccllent S-my pictures it iviis not. ititrotlucctl ou techuiciil groiiritls. Ilttrinpts to obtain ii spritncji of Cliolosclectiin were uumccewftil.


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✍ Hackman, R. H. ;Lemberg, R. 📂 Article 📅 1946 🏛 Wiley (John Wiley & Sons) ⚖ 276 KB

## Abstract Methods for the preparation of Iodoxyl and Diodone, X‐ray contrast substances for the visualisation of the urinary tract, are given. Improved methods of iodination and methylation are described.