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The preparation of functionalized graphene oxide for targeted intracellular delivery of siRNA

✍ Scribed by Yang, Xiaoying; Niu, Gaoli; Cao, Xiufen; Wen, Yuku; Xiang, Rong; Duan, Hongquan; Chen, Yongsheng

Book ID
111949898
Publisher
Royal Society of Chemistry
Year
2012
Tongue
English
Weight
635 KB
Volume
22
Category
Article
ISSN
0959-9428

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✍ Ge Jiang; Kitae Park; Jiseok Kim; Ki Su Kim; Eun Ju Oh; Hyungu Kang; Su-Eun Han; 📂 Article 📅 2008 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 286 KB

## Abstract A novel target specific small interfering RNA (siRNA) delivery system was successfully developed using polyethyleneimine (PEI)–hyaluronic acid (HA) conjugate. Anti‐PGL3‐Luc siRNA was used as a model system suppressing the PGL3‐Luc gene expression. The siRNA/PEI‐HA complex with an averag