✦ LIBER ✦

The preparation of amino-substituted biaryl libraries: The application of solid-supported reagents to streamline solution-phase synthesis

✍ Scribed by Michael G. Organ; Craig E. Dixon

Publisher: John Wiley and Sons
Year: 2000
Tongue: English
Weight: 185 KB
Volume: 71
Category: Article
ISSN: 0006-3592
DOI: 10.1002/(sici)1097-0290(200024)71:1<71::aid-bit10>3.0.co;2-u

No coin nor oath required. For personal study only.

✦ Synopsis

A small library of isomeric benzylamino biaryls was generated in a semi-automated fashion using a solution-phase strategy employing a solidsupported, readily filterable base to facilitate electrophilic substitution followed in sequence by a metal-catalyzed cross-coupling reaction.

📜 SIMILAR VOLUMES

Novel Chemistry of α-Tosyloxy Ketones: A

Novel Chemistry of α-Tosyloxy Ketones: Applications to the Solution- and Solid-Phase Synthesis of Privileged Heterocycle and Enediyne Libraries.

✍ K. C. Nicolaou; T. Montagnon; T. Ulven; P. S. Baran; Y.-L. Zhong; F. Sarabia 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 39 KB

The Sulfoxide Glycosylation Method and I

The Sulfoxide Glycosylation Method and Its Application to Solid-Phase Oligosaccharide Synthesis and the Generation of Combinatorial Libraries

✍ Carol M. Taylor 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 24 KB 👁 2 views

ChemInform Abstract: Polystyrylsulfonyl

ChemInform Abstract: Polystyrylsulfonyl Chloride Resin: An Efficient Solid-Supported Condensation Reagent for the Solution Phase Synthesis of Esters.

✍ N. Zander; R. Frank 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 29 KB 👁 2 views

ChemInform Abstract: Application of Seri

ChemInform Abstract: Application of Serine- and Threonine-Derived Cyclic Sulfamidates for the Preparation of S-Linked Glycosyl Amino Acids in Solution- and Solid-Phase Peptide Synthesis.

✍ Scott B. Cohen; Randall L. Halcomb 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 29 KB 👁 2 views

ChemInform Abstract: An Alumina-Catalyze

ChemInform Abstract: An Alumina-Catalyzed Michael Addition of Mercaptans to N-Anilinomaleimides and Its Application to the Solution-Phase Parallel Synthesis of Libraries.

✍ Soan Cheng; Daniel D. Comer 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 28 KB 👁 2 views

Poly(ethylene glycol) Supported Cinchona

Poly(ethylene glycol) Supported Cinchona Alkaloids as Phase Transfer Catalysts: Application to the Enantioselective Synthesis of α-Amino Acids.

✍ Baptiste Thierry; Jean-Christophe Plaquevent; Dominique Cahard 📂 Article 📅 2003 🏛 John Wiley and Sons ⚖ 98 KB 👁 2 views