𝔖 Bobbio Scriptorium
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The preparation of amino bile acid derivatives

✍ Scribed by A. Hill; P.E. Ross; I.A.D. Bouchier


Book ID
118978821
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
358 KB
Volume
37
Category
Article
ISSN
0039-128X

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Preparation of (Β±)-Ξ±-alkylated amino aci
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Photooxidation of N-methoxy-2.4-disubstituted imidasoles, readily available by way of a three component cyclization followed by 0-allcylation, leads to stable acyl imines whhich react with various organometallics to afford cr,a-disubstituted amino acid m-amides in good yields. In an earlier communi