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The preparation of [14C]-labelled 16-aryloxy prostaglandin f2α analogues. [I.C.I. 81,008 and I.C.I. 80,996]

✍ Scribed by D. F. White

Book ID
102900881
Publisher
John Wiley and Sons
Year
1977
Tongue
French
Weight
563 KB
Volume
13
Category
Article
ISSN
0022-2135

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✦ Synopsis

Abstract

The preparations of [^14^C]‐labelled racemic (95,11R,15R)‐9, 11,15‐trihydroxy‐16‐(3‐trifluoromethylphenoxy)‐17,18,19,20‐tetranor‐5‐cis,13‐trans‐prostadienoic acid [I.C.I. 81,008] from chloro[1‐^14^C]acetic acid and potassium[^14^C]cyanide, and [^14^C]‐labelled racemic (95,11R,15R)‐16‐(3‐chlorophenoxy)‐9,11,15‐trihydroxy‐17,18,19,20‐tetranor‐5‐cis,13‐trans‐prostadienoic acid [I.C.I. 80,996] from chloro[1‐^14^C]acetic acid and potassium[^14^C] cyanide are described.

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