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The Preparation of 1,2,3-Trisubstituted Guanidines

✍ Scribed by Alan R. Katritzky; Niveen M. Khashab; Sergey Bobrov

Publisher
John Wiley and Sons
Year
2005
Tongue
German
Weight
211 KB
Volume
88
Category
Article
ISSN
0018-019X

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✦ Synopsis

Abstract

An operationally straightforward and efficient benzotriazole‐based method for the guanylation of diverse amines by use of the new reagent classes (bis‐benzotriazol‐1‐yl‐methylene)amines 13a–13f and benzotriazole‐1‐carboxamidines 17a–17i is described. The preparation is described for a variety of both acyclic and cyclic 1,2,3‐trisubstituted guanidines in high yields.

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