Highly stereoselective radical addition
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Akio Kayano; Motohiro Akazome; Makoto Fujita; Katsuyuki Ogura
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Article
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1997
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Elsevier Science
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French
β 946 KB
Ettlcient 1.2-asymmetric induction was realized in the addition ot a l-hydroxyalkyl radical (R2(7-OIt) to 3-hydroxy-l-(methylthio)-l-Cp-tolylsulfonyl)-l-alkenes and their acetates (1): Irradiationot l and benzophenone in an 'alcohol (R2CHOH) gave an adduct (2) with a high syn selectivity. Optically