Although reactions between (-)ephedrine E2-(S)-methylamino-l-(R)-phenylpropan-l-017 and RPOC12 (R = Cl, alkyl, aryl, alkoxy, aryloxy) can in principle afford pairs of 1,3,2-oxazaphospholanes eyimeric at phosphorus, most reports describe only one product from highly stereoselective reactions.
The preparation and some reactions of 1,3,2-thiazaphospholidine-2-ones
β Scribed by C. Richard Hall; Nancy E. Williams
- Publisher
- Elsevier Science
- Year
- 1980
- Tongue
- French
- Weight
- 234 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0040-4039
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Twenty-one of the chiral 4-alkoxycarbonyl-2-(β£-alkyl-β£-ethoxycarbonyl methylamino)-1,3-2-thia or oxazaphospholidine-2-ones have been synthesized by cyclization of L-serine or L-cysteine ethyl or n-octyl ester with phosphoryl chloride followed by reaction with a suitable L-amino acid ethyl ester. Pro
## Abstract For Abstract see ChemInform Abstract in Full Text.
A simple, high-yielding synthesis of 2-vinyl-3H-quinazolin-4-one, 2-(1-chlorovinyl)-3H-quinazolin-4-one and 2-(1-bromovinyl)-3H-quinazolin-4-one. The 2-vinylquinazolinones 11a and 14 participate readily in nucleophilic addition reactions. Treatment with both carbon and nitrogen nucleophiles results