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The preparation and purification of ethyl 6-ethyl-4-hydroxy [3-14C] cinnol-3-YL carboxylate (ICI 75,186)

✍ Scribed by S. W. Longworth; D. C. H. Bigg; D. F. White; J. Burns

Publisher
John Wiley and Sons
Year
1974
Tongue
French
Weight
259 KB
Volume
10
Category
Article
ISSN
0022-2135

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✦ Synopsis

Abstract

The preparation of ethyl 6‐ethyl‐4‐hydroxy[3‐^14^C] cinnol‐3‐ul carboxylate (ICI 75,186) from diethyl[2‐^14^C]malonate in five stages is described, together with the purification procedures involved. The overall radiochemical yield, at a specific activity of 3.3 ΞΌCi/mg, was 10%.

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