Preparation of eumelanin-related metabol
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Kazumasa Wakamatsu; Shosuke Ito
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Article
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1988
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Elsevier Science
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English
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5,6-Dihydroxyindole (5,6DHI) and 5,6-dihydroxyindole-2-carboxylic acid (5,6DHI2C) are ultimate precursors of the black melanin, eumelanin. These indolic metabolites and their O-methyl derivatives are excreted in urine of melanoma patients at high levels and of healthy persons at low levels. We descr