The preferred rotamer about the C5—C6 bond of D-galactopyranoses and the stereochemistry of dehydrogenation by D-galactose oxidase
✍ Scribed by Ohrui, Hiroshi; Nishida, Yoshihiro; Higuchi, Hiroko; Hori, Hiroshi; Meguro, Hiroshi
- Book ID
- 115491627
- Publisher
- NRC Research Press
- Year
- 1987
- Tongue
- French
- Weight
- 525 KB
- Volume
- 65
- Category
- Article
- ISSN
- 0008-4042
- DOI
- 10.1139/v87-191
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Differences in rotational isomerism about the C-5-C-6 bond of 4-O-acetyl-6-0-tritylaldohexopyranose derivatives in the &co and 11u1nn0, as compared with the gulucto, series are reflected in different contributions towards diamagnetic shielding of the acetoxyl protons, and rotatory characteristics of
## Abstract An asymmetric synthesis of regio‐ and stereoselectively deuterium‐labelled L‐isoleucine was examined. An unsaturated γ‐lactam readily available from L‐pyroglutamic acid was stereoselectively methylated by the Gilman reagent and subsequent oxidation of the hydroxymethyl moiety afforded a