## Abstract ## Background The aim of this study was to evaluate the influence of coexistent Hashimoto's thyroiditis with papillary thyroid carcinoma on lymph node metastasis. ## Methods The coexistent Hashimoto's thyroiditis group was defined by the presence of thyroid autoantibodies or patholog
The preeminence of growth pattern and invasiveness and the limited influence ofBRAFandRASmutations in the occurrence of papillary thyroid carcinoma lymph node metastases
✍ Scribed by Catarina Eloy; Joana Santos; Paula Soares; Manuel Sobrinho-Simões
- Book ID
- 106118432
- Publisher
- Springer
- Year
- 2011
- Tongue
- English
- Weight
- 199 KB
- Volume
- 459
- Category
- Article
- ISSN
- 1432-2307
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The present study has investigated the functional role of the Met receptor in primary cultures of 20 papillary carcinomas and of normal thyroid cells obtained from the same patients. Normal and tumour cells grew as adherent cells, formed a confluent monolayer after 10-20 days, had epithelial morphol
## Abstract ## BACKGROUND. __BRAF^V600E^__ mutation and p27^kip1^ expression have been introduced as novel indicators that may predict prognosis in different tumors, as well as in papillary thyroid carcinomas. ## METHODS. Tissue samples from 214 consecutive patients who underwent total or near‐t