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The potential to target CCL5/CCR5 in breast cancer

✍ Scribed by Velasco-Velázquez, Marco; Xolalpa, Wendy; Pestell, Richard G

Book ID
127362737
Publisher
Informa plc
Year
2014
Tongue
English
Weight
619 KB
Volume
18
Category
Article
ISSN
1472-8222

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## Abstract CCL5 (previously called RANTES) is in the CC‐chemokine family and plays a crucial role in the migration and metastasis of human cancer cells. On the other hand, the effect of CCL5 is mediated via CCR receptor. RT‐PCR and flow cytometry studies demonstrated CCR5 but not CCR1 and CCR3 mRN