✦ LIBER ✦

The potential role of lysosomes in tissue distribution of weak bases

✍ Scribed by Anna C. Macintyre; David J. Cutler

Publisher: John Wiley and Sons
Year: 1988
Tongue: English
Weight: 862 KB
Volume: 9
Category: Article
ISSN: 0142-2782
DOI: 10.1002/bod.2510090602

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Distribution of lysosomal enzymes in ani

Distribution of lysosomal enzymes in animal tissues

✍ Shibko, S. ;Caldwell, K. A. ;Sawant, P. L. ;Tappel, A. L. 📂 Article 📅 1963 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 721 KB

The term lysosome was originally used by de Duve et al., ('55) to describe a type

Physiologically based pharmacokinetic mo

Physiologically based pharmacokinetic modelling 2: Predicting the tissue distribution of acids, very weak bases, neutrals and zwitterions

✍ Trudy Rodgers; Malcolm Rowland 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 269 KB

A key component of whole body physiologically based pharmacokinetic (WBPBPK) models is the tissue-to-plasma water partition coefficients (Kpu's). The predictability of Kpu values using mechanistically derived equations has been investigated for 7 very weak bases, 20 acids, 4 neutral drugs and 8 zwit

The potentials of MS-based subproteomic

The potentials of MS-based subproteomic approaches in medical science: The case of lysosomes and breast cancer

✍ Agnès Journet; Myriam Ferro 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 1021 KB

## Abstract | I. | Introduction | 00 | | II. | Functions and Biogenesis of the Lysosome | 00 | | III. | Lysosomes and Breast Cancer | 00 | | | A. Lysosomal Hydrolases | 00 | | | 1. Roles of the Lysosomal Enzymes in the Development of Breast Cancer | 00 | | | a. ECM Degradation |

Physical stability of salts of weak base

Physical stability of salts of weak bases in the solid-state

✍ Gregory A. Stephenson; Aktham Aburub; Timothy A. Woods 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 377 KB

When selecting the physical form of an active pharmaceutical substance, there is often a question of when a molecule's pKa renders it too low for salt formation and formulation into a product that will be sufficiently physically stable to provide adequate shelf life. In the paper, a graph is provide

The subcellular distribution of lysosoma

The subcellular distribution of lysosomal hydrolases in the Harding-Passey melanoma

✍ R. Allan Mufson 📂 Article 📅 1974 🏛 John Wiley and Sons 🌐 English ⚖ 815 KB

## Abstract Differential centrifugation of homogenates of Harding‐Passey melanoma demonstrated that aryl sulfatase A and β‐glucuronidase sediment with particles (i.e., lysosomes) distinct from those particles bearing tyrosinase (i.e., melanosomes). The sedimentation curves for the lysosomal enzymes

The role of the concentration and distri

The role of the concentration and distribution of water in the complex permittivity of breast fat tissue

✍ Tarek Said; Vasundara V. Varadan 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 324 KB 👁 1 views

## Abstract The structure of breast tissue is complicated and highly variable and presents a great challenge in the development of physical models that may be used to obtain its effective complex permittivity. Empirical models are commonly used by researchers to fit measured data and extrapolated t