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The potential role of Aurora kinase inhibitors in haematological malignancies

✍ Scribed by Sherif S. Farag

Book ID
108677469
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
528 KB
Volume
155
Category
Article
ISSN
0007-1048

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## Abstract Activating __ras__ mutations are frequently found in malignant tumors of the pancreas, colon, lung and other tissues. RAS activates a number of downstream pathways that ultimately cause cellular transformation. Several recent studies suggested that one of those pathways involves Aurora