The gastrointestinal “hunger” hormone ghrelin is the only known circulating peripheral molecule with the ability to decrease body fat utilization and to increase body weight gain. Accordingly, due to ghrelin’s effects to promote food intake while decreasing energy expenditure ghrelin may offer poten
The potential of ghrelin in the treatment of cancer cachexia
✍ Scribed by Argilés, Josep M; Stemmler, Britta
- Book ID
- 121290689
- Publisher
- Informa plc
- Year
- 2012
- Tongue
- English
- Weight
- 406 KB
- Volume
- 13
- Category
- Article
- ISSN
- 5847-4714
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Ghrelin, the endogenous ligand for the growth hormone secretagogue (GHS) receptor, is critical in the control of food intake and energy balance. The ghrelin receptors are now known to have important physiological properties as modulators of growth hormone release, appetite, glucose homeostasis, meta
Cancer cachexia is highly prevalent in patients with advanced cancer. Its main clinical manifestation is profound anorexia. Progestational drugs have shown meaningful effects on appetite, food intake, and nutritional status in patients with advanced cancer and AIDS, and could be useful in managing a