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The post-platelet 100,000 count: Effects of platelet collection and future

โœ Scribed by Elizabeth A. Jaben; Manish J. Gandhi

Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
57 KB
Volume
26
Category
Article
ISSN
0733-2459

No coin nor oath required. For personal study only.

โœฆ Synopsis

Currently, the majority of platelets transfused in the United States are collected by apheresis. The recent Food and Drug Administration guidance document published maintains that a postdonation platelet count for a donor remain >100,000/lL. During apheresis procedures, platelets are released from the splenic pool into circulation. This allows for higher postdonation platelet counts than anticipated. Some current plateletpheresis instruments take this into account when determining a safe product to be collected. On other instruments, the software does not allow for this correction. This may impact collections, but is expected to be resolved with a software update.

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